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Next-generation Cancer Diagnostics Market: Segmentation, Opportunities, Trends & Future Scope to 2024

The cancer diagnostics industry is projected to witness lucrative growth in the next few years due to the increasing number of technologically advanced products providing accurate test results in the field of diagnostics. Additionally, they also help with therapeutic monitoring and early diagnosis of cancer. Significant improvements observed in the shift from traditional laboratory testing to rapid point of care testing (POC) drive this market. Commercialization of products such as diagnostic kits, instruments, reagents, and consumables plays a role as well. The decreasing cost of genetic sequencing, rising incidence of cancer, increasing interest in the microfluidic hip technology, and the use of circulating tumor cells (CTCs) in cancer management have also aided the development of the next-generation cancer diagnostics market.

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Government measures taken by developed and developing countries to increase the number of research projects in accordance with oncology and preventative diagnosis are anticipated to propel the next-generation cancer diagnostics market over the next few years. The application of tumor diagnostics in the epigenetic analysis and CTC enumeration sectors to monitor tumorigenesis is predicted to make a difference as well. However, the market may be limited by the high laboratory infrastructure costs involved. Insufficient reimbursement policies for innovative technologies and the stringent regulatory procedures and guidelines followed by the government are other factors affecting the global next-generation cancer diagnostics market.

This market is segmented by technology into the following categories: qPCR & multiplexing, protein microarrays, next-generation sequencing (NSG), DNA microarrays, lab-on-a-chip, and reverse transcriptase-PCR (RT-PCR), of which microarrays and PCR are expected to dominate the market due to their rising usage in invitro diagnostics by hospitals and private diagnostics clinics.

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Based on application, the next-generation cancer diagnostics market is classified into the following groups: genetic analysis, biomarker development, epigenetic analysis, and CTC analysis & proteomic analysis, of which biomarkers and CTC analysis are likely to drive the market as these techniques are widely used in drug discovery and development.

The market, in terms of cancer type, is divided into the cervical, breast, colorectal, lung, and other varieties. Its function-based divisions are cancer screening, companion diagnostics, therapeutic monitoring, prognostics, and risk analysis, of which diagnostics and therapeutic monitoring are projected to be the leading segments.

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Single Blood Drop Analysis Market by Application, Trends and Growth Rate to 2026

Global Single Blood Drop Analysis Market: Overview

The drive for single blood drop analysis technologies stems from the need for inexpensive diagnostics for various disease treatment in the healthcare systems across the globe. The technologies can be either electronic or optimal. Single blood drop analysis is obtained from finger prick and is a source of vast repository of biological information. It has opened a new frontier in point-of-care (PoC) technology, thereby paving way for better molecular diagnostics. Single blood drop analysis technologies hold enormous potential in point-of-care diagnostic technologies for detecting various levels of biomarkers, particularly for the management of cancer. PoC assays are rapidly gaining popularity in worldwide healthcare centers, owing to their specificity and sensitivity, apart from their increased user-friendly and affordability. Their significance has been growing alongside with other popular technologies such as nanotechnologies, microfluidics, and biotechnologies.

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The insights in the report offers a critical look at the current outlook, emerging frontiers, key investment pockets, and the changing ecosystem of players. The assessments and evaluations help investors, policymakers, and new entrants gain better understanding of the key evolution trajectories of the global single blood drop analysis market.

Global Single Blood Drop Analysis MarketTrends and Opportunities

Single blood drop analysis technologies are fast gaining traction in cases where high-throughput measurements are required. The application of easy-to-use single blood drop analysis for molecular diagnostics is not limited to diabetes but covers a wide range of disease biomarkers. The rising need for rapid, accurate, and inexpensive disease diagnostics in various clinical settings is a notable trend expected to propel the growth of the market. The rising demand for such diagnostics for self-monitoring at home has also underpinned new growth potential of the market.

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Single blood drop analysis technologies in PoC settings and in the diagnosis of diseases in pediatric patients are fast gaining relevance. The rising role of such technologies in downstream molecular analyses is also expected to substantially expand the prospects of the single blood drop analysis market. Rapidly rising demand for PoC diagnostics in countries with weak healthcare infrastructures is also likely to open new avenues for market players. Large scale developments in nanotechnology and biotechnology in recent years have unlocked promising prospects in the market. The rising use of advanced microfluidic chips in PoC is a notable factor bolstering the expansion of the market. The rising number of genomic research centers in developed and developing regions is a notable factor creating new avenues in the market.

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Craniomaxillofacial Implants Market will Register a CAGR of 6.2% through 2022

With the emergence of resorbable implants, craniomaxillofacial implants are undergoing rapid technological advancement in order to establish an effective treatment platform for facial reconstruction and augmentation. Factors such as growing geriatric population, increasing demand for customized craniomaxillofacial implants, and rising number of road accidents are driving the growth of the global craniomaxillofacial implants market. Furthermore, increasing number of national craniomaxillofacial surgery centers globally that is playing a crucial role in augmenting public awareness about craniomaxillofacial implants and surgery, is another key factor anticipated to support the growth of the craniomaxillofacial implants market. However high cost of the craniomaxillofacial surgery, and lack of appropriate health insurance schemes in developing nations is anticipated to pull back the growth of craniomaxillofacial implants market.

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Based on location, the global craniomaxillofacial implants market has been segmented into internal and external fixators. The internal fixator segment accounted for the largest share of the craniomaxillofacial implants market in terms of revenue in 2013. Lesser infection rates, lower incidence of improper healing and stable nature of internal fixators are the major factors attributed to the leading position of the segment. The internal fixator segment is also expected to grow at the highest CAGR during the forecast period due to improvements in the metallurgical formulation of internal fixators, which have in turn increased their corrosion resistance.

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The composition segment in the craniomaxillofacial implants market has been categorized into calcium ceramics, metals and alloys, polymers, and biologic materials. Metals and alloys was witnessed as the largest segment in terms of revenue in 2013. The dominance of metals and alloys was majorly witnessed due to improved strength to weight ratio, and better biocompatibility and osseointegration property of metallic craniomaxillofacial implants. However, the biologic material segment is expected to foresee fastest growth rate during the forecast period from 2014 to 2022 due to flexible and resorbable nature of the material, which readily takes any anatomical shape as per the requirement. Furthermore, craniomaxillofacial implants made from biologic material are non-toxic in nature with no inflammatory response, hence accelerating the growth of the market segment during the forecast period.

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Infrared Imaging Market: Shares, Strategies and Forecasts, Analysis and Overview upto 2020

The technique of capturing and converting invisible infrared images into visible images is called infrared imaging. Visible light is easily detected by the human eye, but to see infrared light it is important to have infrared cameras and imagers. These devices possess special sensors that operate without the need of visible light. The radiations in the infrared imaging technique are emitted by the targeted objects or are reflected radiations. The imaging devices have infrared illuminator lasers with LEDs (Light Emitting Diodes) for the purpose of illumination. The infrared radiations emitted by warm objects are detected by thermal infrared imagers directing them to infrared sensor array. These sensor arrays convert infrared signals into electric signals which are then converted into an image.

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The distinguishing property of infrared light is that it can penetrate those areas which visible light cannot. Initially developed by the military to produce binoculars, gun lights and night vision cameras, infrared imaging devices are now also used by various civilian agencies. The infrared imaging market has a wide variety of uses and is segmented on the basis of applications in various fields. The infrared imaging technology is used in the field of military and defense for detecting minute details over long distances. It allows aerial vehicles to fly at night time while maintaining near day visibility. In the field of industrial applications, infrared imaging devices are used to monitor temperatures in steel manufacturing processes. In medical treatments, infrared imaging technology is used to detect and quantify small fiber dysfunctions with the help of thermal imaging cameras. Other applications include saving people caught in fire, help wildlife researchers to study warm blooded animals and assist archaeologists to examine artifacts and survey various archeological sites.

Rapid development of high speed infrared cameras with advanced features for measuring thermal performances and evaluating the relative severity of heat is a driver that contributes to the growth of infrared imaging market. Since the applications and innovations of the infrared imaging are on rise, the costs of older applications tend to decrease rapidly which again triggers the use of infrared imaging devices. Another driver that contributes to the growth of infrared imaging market is the continuous development of microbolometer which is used as a detector in thermal cameras. Infrared radiations when strike the detector material changes its electrical resistance.

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This change in resistance is measured and processed into temperatures that are used to create an image. However, the availability of competing technologies like thermal imaging, which is used in military applications where stealth is of utmost importance, acts as a barrier in the growth of this market. Another constraint is the price factor of infrared detectors which limits their use in many sectors. Since infrared detectors are based on the variations in temperatures, they are incapable of detecting differences in objects that have a very similar range of temperatures leading to inaccuracy in results. Companies such as Axis Communications AB, FLIR Systems, Fluke Corporation and Samsung Techwin are some of the major key players in the line of infrared imaging market.

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Demineralized Allografts Market Competitive Strategies And Forecasts to 2024

Bone grafts are generally utilized for bone regeneration, pain relief and structure restoration for decades all over the world. Conservatively, autografts were used for bone grafting, in which patient’s own bone was used as a graft. Autologous bone grafts have proven very useful and is recognized as a gold standard for bone transplant. On the contrary, use of autologous bone grafts embraces the risk of infection transfer. This infection transfer during surgical procedures at both tissue harvesting and transplant sites results in late wound healing and prolonged hospital stay. Therefore, allografts were introduced in the market for overcoming the disadvantages associated with autologous grafts. Allografts possess both osteoinductive and osteoconductive properties, and hence serve as a worthy substitute for autografts.

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Demineralized allografts are also referred as DBMs. Two methods introduced for processing of donor tissue to obtain Demineralized Bone Matrix (DBM) include:

  • Grinding the bones into particulate powder
  • Milling the bones into fibers

DBMs that employ fibers exhibit better osteoconductive scaffold because of their interwoven structure. This interwoven structure gives bone forming cells an opportunity to migrate within the matrix instead of trying to “jump” the gaps between the particles. Demineralized Bone Matrix which uses the fiber technology are engineered in such a way that enhances their properties like osteoconduction. This property is very essential for the quicker healing of the orthopedic tissues after surgery.

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Allografts comprise the tissues, cells and/or proteins that are utilized for implantation, infusion or transplant from donor to the recipient with different genetic makeup of the same species. DBM is the human bone processed with hydrochloric acid that removes the mineral content of the bone. After processing collagen, bone proteins and bone morphogenetic proteins are left. These demineralized allografts exhibit high osteoinductive properties alongside some osteoconductive properties with structural support. Demineralized allografts are readily available world over and are very popular substitutes of the bone autografts. These demineralized bone matrix is often combined with cortical and cancellous bone chips to improve osteoconductive properties. These can be utilized as autologous bone grafts extender in spinal and trauma surgeries. DBM is generally regulated by FDA’ 510K marketing clearing processes. Demineralized allografts if not combined with other materials then only it can be utilized for transplantation. Growth in demineralized allograft market is greater due to anticipated surge in soft-tissue allografts. Increasing demand for repair procedures related to growth in more active lifestyles among affluent younger people. The demineralized allograft market is expected to grow at huge CAGR because of new technological innovations in grafting, and increase in cosmetic surgery, etc. Zimmer has introduced Puros, a demineralized bone matrix which contains ground cortical cancellous chips from the donors.

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The demineralized allografts market can be segmented based on product type, end-users and geography. Based on key product types, the market can be segmented into DBM with cortical bone chip, DBM with cancellous bone chip, DBM with adult mesenchymal stem cells, DBM with calcium sulfate, and DBM with calcium phosphate. Segmentation of this market on the basis of end user can be done as tertiary care hospitals, orthopedics hospitals, orthopedics OPD, and corporate hospitals. The segmentation of the global demineralized allografts market based on geography include regions such as North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.

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Osteosynthesis Devices Market is Projected to Expand at a CAGR of 6.5% Between 2015 and 2023

Osteosynthesis Devices Market

The key factor responsible for the rising demand for osteosynthesis devices is the growing prevalence of osteoarthritis and osteoporosis. Both medical issues have a considerable public health burden as they occur commonly among the geriatric population around the world. The rise in the number of patients suffering from these conditions is directly related to the growing population of the elderly. Osteoarthritis, termed by major medical organizations as one of the leading disabling diseases in developed countries, can add severe limitations to the movement and mobility of a patient. Therefore, treatment of the disease is pertinent to the overall geriatric demographic wellbeing.

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Outside of the elderly population, there are several factors that drastically increase the chances of a patient suffering from osteoarthritis, including obesity and physical injuries. As such, a rise in the number of obese people, especially in developed nations, is a highly concerning factor for healthcare agencies and a major driver for the production and development of osteosynthesis devices. The number of road accidents and sports injuries is also increasing around the world, adding to the probability of an increase in the demand for osteosynthesis devices in the coming years.

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Osteosynthesis devices, however, have quite often been subject to product recalls in recent past, severely reducing their overall usability and market growth.

A culmination of the above factors along with other minor drivers and restraints is likely to result in a CAGR of 6.5% for the global osteosynthesis devices market revenue from 2015 to 2023. By the end of 2016, this revenue is expected to reach US$6.69 bn, and US$11.09 bn by the end of 2023.

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Dental Prosthetics Market Will be Worth US$5.88 bn by 2023

Global Dental Prosthetics Market: Snapshot

The geriatric population exhibits potentially the highest demand for dental prosthetics. It is therefore much likely for the global dental prosthetics market to gain increased traction as the geriatric population grows worldwide. Additionally, the rising number of dental procedures conducted around the world has tipped scales in favor of the global dental prosthetics market. This however, is triggered by the rising incidence of dental disorders. Besides this, on back of rising disposable income, consumers are willing to spend on advanced dental care procedures, which has aided in the market’s expansion in the last few years. With the steadily growing reimbursement facilities for dental procedures, in the near future the demand for dental prosthetics is expected to scale higher than expected.

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It is noted that consumption rate of dental prosthetics is comparatively higher in developing nations. This however is achieved on the back of rising medical tourism. These nations provide advanced healthcare facilities, which is available at a lower price tag hence gaining traction from people around the world. Already a multi-billion dollar industry, the medical tourism sector in developing regions is witnessing a surging demand for dental procedures, which has created an environment conducive to the growth of the dental prosthetics market.

Overall, the global dental prosthetics market, which stood at US$3.5 bn in 2016 is expected to reach US$5.88 bn by the end of 2023, exhibiting a CAGR of 7.6% during the time. On the downside, excessive price competitiveness witnessed in the last couple of years has hindered the market’s trajectory to an extent. Given the scenario players are compelled to offer services at a lower price and provide updated solution. This however creates opportunities for research and development, which could act in favor of the market.

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Demand for Bridges and Crowns to Remain High Through Forecast Period

By type, bridges, veneers, crowns, dentures, and others (including inlays and onlays) constitute the key segments in the global dental prosthetics market. Before 2023 ends, the dental crowns segment is likely to reach US$2.9 bn. As per studies, crowns and bridges are the most commonly used dental prosthetics as they are easy to use and offer a high degree of aesthetics. Moreover, considering the latest development, patients today can choose crowns made from ceramics, plastics, zirconium, and metal ceramics.

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Transparency Market Research (TMR) is a global market intelligence company providing business information reports and services. The company’s exclusive blend of quantitative forecasting and trend analysis provides forward-looking insight for thousands of decision makers. TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources and various tools and techniques to gather and analyze information. Our business offerings represent the latest and the most reliable information indispensable for businesses to sustain a competitive edge.

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Neural Stem & Progenitor Cell Products Market: Analysis and Research Report by Experts 2024

Global Neural Stem & Progenitor Cell Products Market: Overview

The mechanism by which neurons are created through progenitor cells or neural stem cells is known as neurogenesis. During prenatal development, neurogenesis is active and is accountable for populating the brain with neurons. Hormones such as testosterone mainly influence the rate of neurogenesis mechanism. Neural stem and progenitor cells have enough capability to carefully perform pharmacology assessment for drugs designed to impact brain physiology or function. Neural stem cells also show potential in killing numerous cancers and gliomas.

Based on application, the global neural stem and progenitor stem cells market can be segmented into personalized medicines, neural tissue engineering, neurotoxicity testing, drug target validation and testing, cellular therapies for the treatment of central nervous system conditions, and others. In terms of end user, the market can be classified into private labs, commercial labs, government laboratories, and academic labs.

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The report provides a comprehensive analysis of the global neural stem and progenitor cell products market. It does so by providing valuable insights into numerous important parameters of the market including its dynamics, technological developments, geographical landscape, and competitive landscape.

Global Neural Stem & Progenitor Cell Products Market: Trends and Prospects

Since brain disorders are more likely to affect people of old age, the global neural stem and progenitor cell products market will grow mainly due to increased pool of geriatric population.  According to the World Health Organization (WHO), over 14.1% of the world population will be affected by neurological disorders by 2020. The report by the WHO is expected to further boost the market, luring product manufacturers. In addition, enhanced understanding of the nature of neurological diseases and heavy investment in R&D will supplement the growth of the said market.

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Pharmaceuticals is a thriving sector in the global neural stem and progenitor stem cells market. Key pharmaceutical players have shown interest in neural stem cell product development due to their plasticity and ability to develop into the main phenotypes of the nervous system. Its limitless capacity for self-renewal also acts as a plus point. Development of new drugs is costly and bringing new drugs into the market is highly unpredictable, thus, there is mounting pressure on pharmaceutical companies to minimize late-stage product failures. This includes unexpected neurotoxic effects that ascend when candidate drugs enter the clinical testing stages.

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